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February 2024

SkIN Canada Skin Investigation Network of Canada

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Institute of Musculoskeletal Health and Arthritis

SkIN Canada News
Canadian Skin Research Conference
June 25-27, 2024 in Ottawa
 
A joint meeting of the Skin Investigators Network of Canada (SkIN Canada), Skin Research Group of Canada (SRGC), Canadian Dermatology Foundation (CDF), Canadian Skin Patient Alliance (CSPA), and Canadian Society for Investigative Dermatology (CSID), will be held in conjunction with the 99th Canadian Dermatology Association (CDA) Annual Conference. 

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2023 Team Development Award Recipients (New Awards)

Sarah Hedtrich photo

Sarah Hedtrich, The University of British Columbia. Project title: Development of a multi-center research team to explore the potential of anti-mesothelin 1 gene therapies for fibrotic scleroderma.

Aaron Drucker, Women’s College Hospital. Project Title: Using pathology reports to enable population-based studies of rare skin disease.

Regine Mydlarski, University of Calgary. Project Title: Canadian Transplant Dermatology Research Network.

Brett Thombs, Lady Davis Institute for Medical Research of the Jewish General Hospital and Department of Psychiatry, McGill University. Project Title: A New Patient-Researcher Partnership for Research on Itch in Systemic Sclerosis.

Mina Tadrous, Leslie Dan Faculty of Pharmacy, University of Toronto. Project Title: Evidence-based Management of Skin conditions Collaborative (EMSC).

Maryam Piram, Universite de Montreal. Project Title: Auto-inflammatory skin diseases: creation of a Canadian Network (SkinSAIDCanada)

2023 Team Development Award Recipients (Renewals)

Caitlin Champion, NOSM University. Project Title: Canadian Frostbite Collaborative National Website Development.

Carolyn Jack, McGill University. Project Title: Canadian Patient-Oriented Dermatitis Database and Biobank (C-POD).

Elena Netchiporouk, Research Institute of the McGill University Health Center. Project Title: Canadian Morphea Registry (C-MORE): Characterizing the landscape of morphea in Canada and elucidating predictors of severe disease.

Lucie Germain, Université Laval. Project Title: A multicenter collaborative skin research group focusing on novel treatment for epidermolysis bullosa.

Mélanie Laurin, Université Laval: Project Title: Development of a in vivo mouse screening platform to identify molecular effectors of non-melanoma skin cancers.

Timothy Hanna photo

Timothy Hanna, Queen’s University. Project Title: A Multi-Province Platform for Merkel cell carcinoma Health Services Research.

Can SkIN Canada help?

Request support for your study

 

SkIN Canada has launched a formal study intake process for investigators requesting support from the Network. Please visit our  RESOURCES page for more information on how we can help with funding, patient engagement, database creation, project administration, ethics application, or statistical support.

Submit Intake Form 

From the Training Committee Hub

Skin Canada Travel and Mobility Awards –

Application Deadline May 15, 2024

1. The deadline for the next SkIN Canada Trainee Travel Award is Wednesday May 15 (2024) before 11:59 PM ET. SkIN Canada provides partial funding for trainees to attend conferences as part of their training experience. A limited number of awards are available each year on a competitive basis. Applicants who have previously received funding through this program in a fiscal year are not eligible to receive funding until the following fiscal year. The value of the SkIN Canada Travel Award is a maximum of $1,000 CAD. 

 

2. The deadline for the next SkIN Canada Trainee Mobility Award is Wednesday May 15 (2024) before 11:59 PM ET. The SkIN Canada Trainee Mobility Award provides funding for trainees in the field of skin research to study and conduct research for a brief period in a laboratory other than their own within Canada or abroad as part of their training experience. A limited number of awards are available each year on a competitive basis.  There will be two competition periods per year, one in May and one in October. Applicants are eligible for the award only once during a particular training period or level of study (e.g. MSc, PhD, Clinical residency, or Postdoctoral training).
        The value of the Skin Canada Trainee Mobility Award is up to $4,000 which can be used for the trainee’s research in a host laboratory within Canada or abroad for a period ranging from 2 weeks to 6 months. 

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Skin Canada Training Committee

The Training Committee represents skin research trainees from across Canada and considers regional representation to be valuable. The committee currently has an opening for a PhD student or a post-doctoral fellow from any of the Western Provinces. If interested in joining this dynamic committee, please send your expression of interest and CV  to info@skincanada.org.

Workshops of Interest to Skin Research Trainees

The Annual Skin Canada Workshops will be held at the upcoming Canadian Skin Research Conference in Ottawa (June 25-27, 2024). The workshop topics will include ‘patient engagement’ and ‘Skin of Color Research’. All trainees are encouraged to participate. There is no registration fee.

The next SkIN Canada Training Committee Meeting will be held on Thursday March 21st.

 

News from other Organizations

Genodermatoses Network Meeting

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Open Call: Participation in Project on Indigenous Patients with Atopic Dermatitis
 
This is an open call for those interested in helping to develop a proposal involving formation of a national east-west collaborative interdisciplinary engagement initiative and culturally safe model aiming to improve care for Canadian Indigenous peoples living with or caring for those with atopic dermatitis. Co-PIs include Drs. Rachel Asiniwasis (University of Saskatchewan), Carolyn Jack (McGill), and Derek Chu (McMaster). 


Please forward your CV to remotederm@outlook.com, particularly if you have experience with:
•    public and community health
•    qualitative and mixed-methods research
•    CIHR grant writing
•    Indigenous health and skin of colour
•    using guidelines involving meaningful and culturally safe practices and plans. 

The team is also looking for another Co-PI from BC or Alberta.


 

Keen-on Healing Fibrosis Symposium –
October 18-19 2024

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Request for Standing Offers: Post-Market Drug Evaluation Program

Canada’s Drug and Health Technology Agency (CADTH) has a Post-Market Drug Evaluation Program (PMDE) that focuses on providing answers to questions about the safety and effectiveness of drugs, whether they are existing or new products.  The program has been designed to maximize CADTH’s access to a wide range of applied researchers, data analysts, and methodologists from across Canada. To meet future needs, the PMDE program has launched a Request for Standing Offers process to recruit more individuals and teams to join CoLab, their network of researchers. 

 
Pfizer Global Medical Grants – Request for Proposals
 
Pfizer Global Medical Grants (GMG) supports the global healthcare community’s independent initiatives (e.g., research, quality improvement, or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Specific Area of Interest:  Projects that will be considered for Pfizer support will focus on educational programs addressing knowledge and practice gaps specific to the overall care management of atopic dermatitis (AD), Alopecia Areata (AA), or Vitilgo. If you have questions regarding this RFP, please direct them in writing to Sue Lee, Grant Officer (sue.lee@pfizer.com). Application Due Date: Monday April 15, 2024.
 

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Recent Publications by SkIN Canada Members
 
Inflammatory Skin Conditions
  1. Zabihi H, Shojaei D, Seigel K, Al-Dehneem R, Piguet V, Croitoru DO. Evaluating the Clinical Utility of Sulfasalazine in the Treatment of Pyoderma Gangrenosum: A Systematic Review. J Cutan Med Surg. Mar 10 2024:12034754241238713.https://www.ncbi.nlm.nih.gov/pubmed/38462891
  2. Metko D, Mehta S, Piguet V. Cannabis Usage Among Patients With Hidradenitis Suppurativa: A Scoping Review. J Cutan Med Surg. Mar 10 2024:12034754241238719.https://www.ncbi.nlm.nih.gov/pubmed/38462895
  3. Riaz S, Emam S, Wang T, Gniadecki R. Negative impact of comorbidities on all-cause mortality of psoriasis patients is partially alleviated by biologic treatment: A real-world, case-control study. J Am Acad Dermatol. Feb 20 2024.https://www.ncbi.nlm.nih.gov/pubmed/38387852
  4. Chu AWL, Wong MM, Rayner DG, Guyatt GH, Diaz Martinez JP, Ceccacci R, Zhao IX, McMullen E, Srivastava A, Wang J, Wen A, Wang FC, Brignardello-Petersen R, Izcovich A, Oykhman P, Wheeler KE, Wang J, Spergel JM, Singh JA, Silverberg JI, Ong PY, O’Brien M, Martin SA, Lio PA, Lind ML, LeBovidge J, Kim E, Huynh J, Greenhawt M, Gardner DD, Frazier WT, Ellison K, Chen L, Capozza K, De Benedetto A, Boguniewicz M, Smith Begolka W, Asiniwasis RN, Schneider LC, Chu DK. Systemic treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials. The Journal of allergy and clinical immunology. Dec 2023;152(6):1470-1492.https://www.ncbi.nlm.nih.gov/pubmed/37678577
  5. Machlab K, Yeung J, Gooderham M. Risankizumab in Adults with Psoriatic Arthritis. Skin Therapy Lett. Nov 2023;28(6):1-6. https://www.ncbi.nlm.nih.gov/pubmed/38015960
 

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Wound Healing, Fibrosis and Regeneration

  1. Khalaf F, Hutter MF, Jeschke MG. Traversing the blaze: Uncovering the challenges in burn care for older adults. Surgery. Oct 11 2023.https://www.ncbi.nlm.nih.gov/pubmed/37833154
  2. Sanchez-Espino LF, Sibbald C, Stimec J, Laxer RM, Pope E. Characteristics and onset of presentation of pediatric stiff skin syndrome: A retrospective cohort study of 11 patients in a tertiary care center. Pediatr Dermatol. Oct 20 2023.https://www.ncbi.nlm.nih.gov/pubmed/37864376
  3. Sierra-Sanchez A, Magne B, Savard E, Martel C, Ferland K, Barbier MA, Demers A, Larouche D, Arias-Santiago S, Germain L. In vitro comparison of human plasma-based and self-assembled tissue-engineered skin substitutes: two different manufacturing processes for the treatment of deep and difficult to heal injuries. Burns Trauma. 2023;11:tkad043.https://www.ncbi.nlm.nih.gov/pubmed/37908563
  4. Matthewman J, Tadrous M, Mansfield KE, Thiruchelvam D, Redelmeier DA, Cheung AM, Lega IC, Prieto-Alhambra D, Cunliffe LA, Mulick A, Henderson A, Langan SM, Drucker AM. Association of Different Prescribing Patterns for Oral Corticosteroids With Fracture Preventive Care Among Older Adults in the UK and Ontario. JAMA Dermatol. Aug 9 2023.https://www.ncbi.nlm.nih.gov/pubmed/37556153
  5. Yang Y, Gomez N, Infarinato N, Adam RC, Sribour M, Baek I, Laurin M, Fuchs E. The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates. Nature cell biology. Jul 24 2023.https://www.ncbi.nlm.nih.gov/pubmed/37488435

 

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Skin and Other Cancers
 
  1. Huang Y, Fleming P, Fung K, Chan AW. Association between dermatology follow-up and melanoma survival: a population-based cohort study. J Am Acad Dermatol. Feb 16 2024.https://www.ncbi.nlm.nih.gov/pubmed/38368952
  2. Venables ZC, Gran S, Levell NJ, Yiu ZZN, Proby CM. International melanoma and non-melanoma skin cancer mortality trends – is it time to re-focus our attention? Clin Exp Dermatol. Dec 7 2023.https://www.ncbi.nlm.nih.gov/pubmed/38060677
  3. Mohsen ST, Price EL, Chan AW, Hanna TP, Limacher JJ, Nessim C, Shiers JE, Tron V, Wright FC, Drucker AM. Incidence, Mortality, and Survival of Merkel Cell Carcinoma: A Systematic Review of Population Based-Studies. The British journal of dermatology. Oct 24 2023.https://www.ncbi.nlm.nih.gov/pubmed/37874770
  4. Joly-Chevrier M, Aly S, Lefrancois P. Quality Assessment of Skin Cancer Videos Calls for Improved Patient Content: A YouTube Cross-Sectional Study. J Cutan Med Surg. May 24 2023:12034754231174847.https://www.ncbi.nlm.nih.gov/pubmed/37226286
  5. Mirali S, Tang E, Drucker AM, Turchin I, Gooderham M, Levell N, Beecker J, Bissonnette R, Catherall H, Lapointe McKenzie JA, Hawkins N, Hong CH, Kalia S, Papp K, Chan AW. Follow-up of Patients With Keratinocyte Carcinoma: A Systematic Review of Clinical Practice Guidelines. JAMA Dermatol. Jan 1 2023;159(1):87-94.https://pubmed.ncbi.nlm.nih.gov/36322063/
 
 

Other
 
  1. Martindale APL, Ng B, Ngai V, Kale AU, Ferrante di Ruffano L, Golub RM, Collins GS, Moher D, McCradden MD, Oakden-Rayner L, Rivera SC, Calvert M, Kelly CJ, Lee CS, Yau C, Chan AW, Keane PA, Beam AL, Denniston AK, Liu X. Concordance of randomised controlled trials for artificial intelligence interventions with the CONSORT-AI reporting guidelines. Nature communications. Feb 22 2024;15(1):1619.https://www.ncbi.nlm.nih.gov/pubmed/38388497
  2. Weng J, Zhou LL, Hahn T, Shojania K, Dutz J. Adult-Onset Still Disease After ChAdOx1 nCOV-19 Vaccination. J Rheumatol. Feb 2023;50(2):290-291.https://pubmed.ncbi.nlm.nih.gov/35970527/
  3. Tafech B, Mohabatpour F, Hedtrich S. Surface modification of lipid nanoparticles for gene therapy. J Gene Med. Dec 3 2023:e3642.https://www.ncbi.nlm.nih.gov/pubmed/38043928
  4. Pope E, Lara-Corrales I, Rehmus W, Ramien M, Spring S, McCuaig C, Fiorillo L, Sibbald C, Bergman J. Pediatric Dermatology in Canada: A Broad Review of Population Needs, Workforce and Training With Proposed Solutions. J Cutan Med Surg. Oct 12 2023:12034754231204865.https://www.ncbi.nlm.nih.gov/pubmed/37823355
  5. Loewa A, Feng JJ, Hedtrich S. Human disease models in drug development. Nat Rev Bioeng. May 11 2023:1-15.https://www.ncbi.nlm.nih.gov/pubmed/37359774
 

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