Dr. Philippe Lefrancois (MD, PhD, FRCPC, DABD) is an Assistant Professor in the Department of Medicine, Division of Experimental Medicine, at McGill University. His laboratory focuses on enhancing understanding of skin cancers, particularly Basal Cell Carcinoma (BCC), which is the most prevalent of all human cancers. The aim is to enable patients to benefit from new targeted therapies and management options. The research involves defining the cellular and molecular phenotypes of aggressive BCC tumors. Computational biology, genomics, and molecular biology approaches are employed using various sample types, including data from cancer consortia, patient-derived tumors, publicly-available sequencing data from other patient cohorts, and primary cancer cell lines. The emphasis is on identifying novel signaling pathways and actionable targets for BCC, as well as characterizing the BCC tumor microenvironment with a focus on clinically-relevant features.
Webinar Title: Tips & Considerations to Incorporate Genomics Into Your Skin Research Projects
Dr. David Croitoru (MD MSc FRCPC DABD) is a clinical associate at Women’s College Hospital (Toronto) specializing in complex medical dermatology and wound care. He completed his residency training at the University of Toronto Division of Dermatology as co-chief resident with a concomitant master’s in the Graduate Department of Immunology. He is the clinical lead of the only specialized clinic for patients with Pyoderma Gangrenosum in Canada and conducts translational research in prospective cohorts of neutrophilic inflammatory and connective tissue disease.
Webinar Title: Novel Immune Targets in Pyoderma Gangrenosum
Dr. Amani Hassan did her undergraduate studies at the Lebanese University, Faculty of Arts and Sciences in Beirut, Lebanon (2004-2007). She then pursued her Master’s degree in Biochemistry at the American University of Beirut, in Lebanon (2007-2009).
She holds another Master’s degree in Molecular Biology from the Institute of Research in Cancer and Immunology (IRIC) affiliated with the University of Montreal (2009-2010). Amani did her PhD in Biomedical Sciences at CHU Sainte Justine Research Center, affiliated with the University of Montreal (2013-2018). She is currently a postdoctoral fellow in the Surgical and Interventional Sciences Program at McGill University under the supervision of Dr. Anie Philip.
Webinar Title: Establishment of tumor organoids from head and neck squamous cell carcinoma to study dysregulation of signaling pathways and response to therapy.
Powerpoint Presentation to be added at a later date
Lab Info
Name:
Biobank LOEX
Principal investigator:
Ms. Veronique Moulin
Location:
Quebec, Quebec
Contact:
Veronique Moulin
veronique.moulin@fmed.ulaval.ca
Objective/description
The advancement of biomedical research including regenerative medicine, tissue engineering reconstruction of different tissues and organs as well as the understanding of physiological, pathophysiological mechanisms and pharmacotoxicological and cosmetological analyzes.
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Lab Info
Name:
Piguet Lab
Principal investigator:
Dr. Vincent Piguet
Location:
Toronto, Ontario
Contact:
David Croitoru
David.croitoru@mail.utoronto.ca
Objective/description
We are engaged in translational research of inflammatory dermatoses and perturbation of immune regulation and microbial communities at associated disease sites.
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Lab Info
Name:
CTTB Biobank and Registry for Atopic dermatitis
Principal investigator:
Dr. Carolyn Jack
Location:
Montreal, Quebec
Contact:
Gaurav Isola
gaurav.isola@mail.mcgill.ca
Objective/description
The Transdisciplinary Centre for Biological Therapies (Centre Transdisciplinaire de Thérapies Biologiques or CTTB) is a multidisciplinary, integrated approach for patients who are receiving therapies directed at the immune system. The CTTB Biobank and Registry for Atopic dermatitis has been created to collect and store blood, skin tissue and other types of biological samples, as well as clinical information, for current and future research purposes.
Objectives:
To identify the impact of various treatments for dermatitis on patient symptoms, quality of life and disease outcome.
To characterize (including potential sequencing) skin lesions and matched normal tissues at the molecular and cellular level (the cells, the DNA, RNA and proteins, as well as their regulatory factors), to help better understand disease biology, prognosis and response to therapy, with a potential to identify new targets for improved treatments.
To characterize cells, proteins and genetic material (RNA and DNA) in the blood or other bodily fluids to identify characteristics that may act to identify specific kinds of skin diseases, or to predict response to therapy or disease outcome.
To characterize biomarkers, including those related to microbiome (bacteria that live on or in humans) to identify potential disease markers, markers of response to therapy or prognostic markers.
Collection Details
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