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Canadian Atopic dermatitis Cohort for Translational Immunology and imaging (CACTI) BRONTE trial (BROadband vs Narrowband phototherapy for eczema)

Women’s College Hospital
3 Sites
ON, QC, BC

Drs. Aaron Drucker

Position: Member

The CACTI project is a multicenter observational prospective cohort study based at three Canadian institutions (Women’s College Hospital/University of Toronto, McGill University Health Science Centre, University of British Columbia). It will enroll patients with severe atopic dermatitis with inadequate control from topical therapy and collect biospecimens (blood, microbial swabs, skin biopsies) from consenting participants. It also contains a nested randomized controlled trial comparing two types of phototherapy. This project requires a secure online data platform to collect and centrally store unidentified longitudinal clinical data for participants across the three sites. The central study site is Women’s College Hospital, making a partnership with SkIN Canada seamless. Each site will enter their own data into the database. The platform must also be able to randomize patients eligible for the nested randomized controlled trial. It must also be able to document and track biospecimens collected at the different sites. It should also be able to track storage and laboratory analyses of these samples.

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